6th Edition of Neurology World Conference 2026

Speakers - NWC 2023

Saeede Zarei, Neurology World Conference, Miami, USA

Saeede Zarei

Saeede Zarei

  • Designation: QC lead, Puretek Corp
  • Country: USA
  • Title: Genomic Characterization and Molecular Mechanisms in Glioblastoma Multiforme and Current Treatment Strategy

Abstract

Glioblastoma (GBM) is the most aggressive malignant primary brain cancer, with an incidence rate of 3.9 per 100,000 persons in the United States and a median age of 64 years. GBM has an average life expectancy of one year. This is mostly due to the highly muted genome of GBM, which is characterized by the deregulation of many key signaling pathways involving growth, proliferation, survival, and apoptosis. In this review, I try to summarize the molecular mechanisms that have led to the GBM and discuss the potential therapeutic strategies and approaches.